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and it regulates the transcriptome by activating or repressing hundreds of direct target genes
TREM2 plays a role in chronic inflammation and can stimulate the production of constituent rather than inflammatory chemokines and cytokines
It has been shown to interact with heterotrimeric G proteins
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M6PR Recombinant Rabbit mAb (S-2348-14) Interleukins and it regulates the transcriptomeProduct Specification Host Rabbit Antigen M6PR Synonyms Cation independent mannose 6 phosphate receptor; CI Man 6 P receptor; CI MPR; 300 kDa mannose 6 phosphate receptor (MPR 300); Insulin like growth factor 2 receptor; Insulin like growth factor II receptor (IGF II receptor); M6P IGF2 receptor (M6P IGF2R); CD222; MPRI; IGF2R Immunogen Synthetic Peptide Location Golgi apparatus membrane Accession P11717 Clone Number S 2348 14 Antibody Type